Cell interactions in abnormal structures in aged kidneys: Potential therapeutic target for chronic kidney disease

Chronic kidney disease is a condition in which kidney function declines, causing significant health issues in patients. A previous study led by Dr. Motoko Yanagita found that tertiary lymphoid tissues (TLTs), which develop in several kidney diseases, inhibit the repair of kidney injury and are associated with poorer prognosis connected to the development of chronic kidney disease. A new study investigated the role of TLTs in exacerbating kidney injury and the study’s findings were published in the Journal of the American Society of Nephrology.