Investigating the laterality of blood pressure regulation during cardiovascular disease progression

The outcomes of blood pressure regulation provide a clear picture of the underlying mechanisms of the arterial baroreflex, a critical cardiovascular reflex, during health and disease. Under normal blood pressure, the functional difference can vary between the left vs. right aortic baroreceptor, a type of mechanoreceptor or special nerve ending used to relay information derived from blood pressure within the autonomous nervous system, and regulate blood pressure within a preset range. Nevertheless, much is unknown regarding the laterality or dominance of left vs. right regions of aortic baroreflex function under high blood pressure.