Parkinson’s disease - ADVANCED MEDICAL TECHNOLOGIES

Scientists worldwide are trying to find a cure for Parkinson’s disease because existing drugs can neither prevent neuronal death nor slow or stop its progression. Fortunately, Stem Cell Therapy — high-tech technology has the potential to patients with this neurological disease.

Parkinson’s disease is a neurodegenerative disease that affects the neurons in the brain. According to statistics, 140 cases of morbidity are diagnosed per 100,000 people.

Genetically inherited problems cause about 5% of cases, but it is unclear what causes the remaining 95% of cases.

Doctors identify predisposing factors that increase the risk of developing the disease. The following are among them:

Natural aging. Age-related changes contribute to a decrease in the number of nerve cells. As a result, dopamine levels in the basal ganglia decrease. This is considered a provoking factor for the development of Parkinson’s disease.
Impact of adverse environmental factors. The death of nerve cells can occur due to ingesting toxic substances, heavy metals, and free radicals into the body.
Intake of certain medications. Violation of dopamine metabolism can provoke some drugs. As a result, pathological symptoms similar to Parkinson’s disease appear.
Burdened heredity. The gene responsible for the transmission of Parkinson’s disease has not yet been identified. However, in 20% of cases, if one of the relatives was diagnosed with the disease, subsequent generations are at risk.

Symptomatology

Parkinson’s disease is characterized by both motor symptoms (tremors, slowed movements, muscle stiffness, balance and posture problems, loss of automatic movements, and difficulties with speech and writing) and non-motor signs and symptoms (depression, anxiety, memory and attention impairment, and sleep disorders ).

Tradition treatment Parkinson’s disease

It is vital to understand the fact that traditional treatment of Parkinson’s disease applied worldwide is so far only symptomatic. The medications used cannot eliminate the symptoms that have happened. If this happened, it is no longer possible, for example, to restore the sense of smell, and remove trembling in the arm and stiffness in the shoulder. All therapy is aimed to restore the balance of neurotransmitters in the brain. It is believed that the level of dopamine in the intercellular space decreases due to various reasons. The drugs are aimed to raise it only. Although medications can reduce movement disorders, the disease itself continues to develop.

Parkinson’s disease makes it difficult for patients to carry out their daily activities and is the second most common cause of dementia.

Stem Cell Therapy can help not only to slow down the development of Parkinson’s disease but also in a number of cases significantly its symptoms!

Stem Cell Therapy for Parkinson’s disease

Regenerative Stem Cell Therapy can help patients with different stages of the disease.

The potential for use of Stem Cells in the treatment of diseases of the Central Nervous System (including Parkinson’s disease ) lies in their main property, which is called differentiating potential. Upon receiving a neural signal about damage to one or another part of the body, the brain sends a portion of Stem Cells to the so-called «lesion focus» and there they transform into cells of damaged nervous tissues, replacing the sick ones. The treatment has a powerful immunomodulatory effect, which helps stop the disease’s progression and destroy the nerve fibres’ structure.

In other words, Stem Cells can independently find the source of damage and the cause of the malfunctioning of the organs and systems of the body. They migrate to the source of the problem and cause a whole cascade of regenerative reactions there, restoring damaged functions. Thus, unlike other conventional methods of treatment, Stem Cell Therapy acts not only on the symptoms but also on the cause of the disease! This fact allows the use of Stem Cell Therapy to help patients with diseases, the exact reason for which is still unknown to modern science, including for the treatment of Parkinson’s disease.

The expected outcomes of Stem Cells Therapy for Parkinson’s disease :

Minimal tremors and reduced rigidity.
Reduced involuntary movements.
Ability to do routine activities without much difficulty.
Ability to walk for longer distances.
Increased independence during daily activities.
Improved speech.
Improved swallowing.
Overall improvement assessed by the unified Parkinson’s disease rating scale.
No need to enhance traditional drug therapy.
Improving cognitive functions and preventing the development of dementia.

Stem Cells therapy is one of the most modern and promising methods to help patients with Parkinson’s disease. This is a high-tech technique, the safety and effectiveness of which have been confirmed by `

Having more than 10 years, specialists at our clinics have developed a unique method of combined treatment of Parkinson’s disease with Stem Cells from different sources within one visit to the clinic.

Given the fact that in most cases of PD occurs in elderly patients, it does not make sense to use the patient’s own (autologous) Stem Cells for its treatment. Stem Cells undergo aging processes in the same way as other body cells. Thus, their healing ability to restore the lost functions of the body is small. Therefore, young and active donor Stem Cells are used in most cases. They are individually selected from our certified biobanks, safe and effective.

3 ways to introduce Stem Cells into the patient’s body: are used for patients with Parkinson’s disease (PD):

Intravenous
Intrathecal
Intranasal.

With this simultaneous administration, Stem Cells from different sources enhance each other’s therapeutic effect and increase the duration of the treatment effect. The combination of several routes of administration allows the transport of Stem Cells to all target organs (central and peripheral nervous system, muscular apparatus). There they cause a whole cascade of regenerative processes. As a result, activation and formation of new cells of the nervous tissue occur, which replaces the damaged areas of the nervous tissue, providing a therapeutic effect on all symptoms of the disease.

The intravenous way of administration ensures the penetration of Stem Cells with blood flow to all organs and tissues of the body that are weakened by the disease and cause the normalization of the functioning of all body systems. Stem Cells are present in every human body. However, their introduction in dosage millions of times higher than their normal amount in the body allows them to restore the myelin sheath of the affected nerve fibers and stops the overreaction of the immune system that this lesion causes. Such a large number of Stem Cells allows them to distribute not only in the central nervous system but also throughout the body, improving the function of all systems and organs. In addition, clinical studies have found that the introduced Stem Cells can be modified (differentiated) into other cells, including nerve cells. By modification, Stem Cells are embedded between the cells of the nerve bundles, thereby replacing all the affected areas. This restores the process of transmitting the nerve impulse and leads to the reverse development of symptoms of the disease.
With intrathecal administration, Stem Cells are injected directly into the spinal space of the vertebral column. Thus, with the current of cerebrospinal fluid, they penetrate the blood-brain barrier and are fixed directly in damage to the brain and motor neurons. There, they stimulate regeneration processes, slow down the progression of the disease, and in some cases, restore lost functions. The introduction of Stem Cells into the spinal space slows down the process of destruction of motor neurons and promotes partial restoration of the structure of the spinal cord. Replacing dead neurons, Stem Cells reduce symptoms and improve motor disorders without causing a negative immune response in the body.
The intranasal way is the introduction of Stem Cells and exosomes (concentration of regenerative substances that produce Stem Cells) to the patient by inhalation. In this way, the introduction of Stem Cells and exosomes penetrates directly into the brain through the vascular network of the nasal sinuses. The method can be used for the correction of cognitive manifestations of the disease: it improves behavioral responses, speech, attention, mood, sleep, social adaptation, and most importantly, it is very well tolerated by patients.

Stem Cells Therapy program for Parkinson’s disease also includes complex physiotherapeutic procedures that improve the penetration of Stem Cells into the damaged areas and create conditions for their long-term functioning (hyperbaric oxygen therapy, electrical stimulation, reflexology, etc.).

The minimum duration of the program is 3 days. The procedure is performed on an outpatient basis, but if necessary or if desired by the patient, the program can be performed on an inpatient basis

IMPORTANT INFORMATION!

Depending on the patient’s condition (the stage of disease, the presence of complications and concomitant diseases, etc.), the doctors of our clinics can make changes and additions to the treatment program according to the patient’s needs.

We warn that the effectiveness of Stem Cell Therapy depends on many factors (the patient’s age, concomitant diseases and complications, individual characteristics of the body, genetic predisposition, lifestyle, etc.), so the expected result of treatment may differ from the actual result. In addition, we draw attention to the fact that the recovery of patients after Stem Cell Therapy should be implemented as part of a comprehensive approach to the treatment. Stem Cell Therapy can be combined with other therapeutic methods. This increases the effectiveness of the main therapy. Therefore, we recommend that you continue your rehabilitation and follow all your doctor’s advice on drug treatment of the disease in parallel with Stem Cell Therapy. This is a crucial point for achieving a sustainable result.

We provide the most comfortable conditions of stay and excellent client service to our patients:

free transfer (the patients are taken to the Clinic from railway stations or airports and back);
selecting and booking the most transport-accessible hotel (only accommodation is paid);
оur clinics have facilities for the comfortable stay of people with disabilities.

Our clinics have everything you need for treatment: our laboratory for the cultivation of Stem Cells, biobanks for storage, and the best specialists in Regenerative medicine who constantly improve their skills to help our patients with the most modern and safe methods.

We try to make our patients feel at home in the clinic and the entire treatment process goes smoothly.

You need to consult with the doctors to get complete information about the possibility of Stem Cell Therapy specifically in your case. Sign up for a free consultation with the specialists of the clinic and give yourself the opportunity to live an active and full life!

We will do our best to help you!