HomeБез рубрикиRare leptin variants found in two children, leading to hyperphagia and obesity
Rare leptin variants found in two children, leading to hyperphagia and obesity
An international team of doctors and medical scientists has found two rare leptin variants in two children. Both variants led to hyperphagia and obesity. In their study, reported in The New England Journal of Medicine, the group found mutations in genes responsible for leptin production and explored how they impacted eating behavior in the patients.