Researchers gain structural insights into the immune modulator Siglec-15 and its interaction with T cells

Siglec-15 has emerged as a promising target for therapeutic intervention in the field of cancer treatment, primarily due to its unique expression pattern and potential as an immune modulator. Its distinct expression profile, often found in tumor cells and tumor-associated macrophages, makes it an attractive candidate for targeted therapies aimed at modulating immune responses within the tumor microenvironment.