Treatment of Cerebral Palsy is a complicated task. Treatment is a lifelong process since it is impossible to cure the disease completely. But this does not mean that the diagnosis of Cerebral Palsy is a sentence. Fortunately, Stem Cell Therapy is one of the most promising ways of helping patients with Cerebral Palsy.
Cerebral Palsy (CP) refers to a group of chronic motor disorders caused by brain damage. The most common cause of the disease is damage to the child’s brain cells as a result of oxygen starvation during hypoxia or trauma in the prenatal or postnatal period. If the focus of cell death affects the brain area responsible for movement, this will likely lead to the development of Cerebral Palsy. Less commonly, the cause of Cerebral Palsy may be an abnormal brain development caused by genetic factors.
Usually, the first symptoms occur immediately after the child’s birth but may appear later as the child grows and develops.
There are several forms of the disease:
- Dyskinetic (hyperkinetic)
Each of the forms has its clinical manifestations, but the most common symptoms are:
- Movement disorders associated with changes in muscle tone (increase in the form of spasm or decrease in the form of paresis or paralysis).
- Loss of coordination and difficulty performing tasks that require the involvement of fine motor skills: writing, holding objects, etc.
- The appearance of involuntary movements.
- In severe cases, cognitive impairment and delayed psycho-speech development.
The traditional way of treatment
Treatment of Cerebral Palsy is a complicated task. It is right to say that this is not a treatment but rather a rehabilitation focused on restoring functions that have suffered from the disease. Rehabilitation must be carried out comprehensively and continuously. In this way, not only motor but also speech, communicative, and intellectual skills can be corrected.
Massage is the most accessible method of rehabilitation. It helps to relieve spasms and improve muscle tone. It is also necessary to use therapeutic exercises during the rehabilitation of Cerebral Palsy. They improve coordination of movement and, if performed regularly, give a good result. Special robot simulators help to diversify and facilitate the implementation of lead-ups.
In the absence of general contraindications and a predisposition to seizures, physiotherapeutic procedures can be used. For example, myostimulation with electrophoresis has a good effect. Many therapists recommend electroreflexotherapy to increase the activity of neurons in the cerebral cortex, reduce muscle tone, and improve coordination, speech, and diction.
In addition to rehabilitation procedures, drug therapy is used to improve blood supply and oxygenation of the brain and the functioning of the elements of the cortex.
Stem Cell Therapy for Cerebral Palsy
Although rehabilitation procedures are being improved every year (for example, virtual reality motion simulators have appeared), it is vital to understand that they can only improve symptoms but will not lead to a cure for Cerebral Palsy. Treatment is a lifelong process since it is impossible to cure the disease completely. But, this does not mean that the diagnosis of Cerebral Palsy is a sentence. Influencing the symptoms and cause of the disease is vital for sustainable positive results. Stem Cell Therapy has this potential.
The specialists of our clinic have developed a unique approach to treatment for Cerebral Palsy — Stem Cell Therapy.
It includes using the regenerative properties of Stem Cells, neurostimulation carried out on our unique equipment (NeuroPort, NeoStim), physiotherapy, and individually selected physical rehabilitation. Only such an integrated approach is the key to success!
Stem Cell Therapy is one of the most promising approaches to treating Cerebral Palsy.
This is a high-tech technique, the safety, and effectiveness of which have been confirmed by numerous clinical studies.
The potential of Stem Cells use in the treatment of diseases of the Central Nervous System (including Cerebral Palsy) lies in their main property of differentiating potential. Upon receiving a neural signal about damage to one or another part of the body, the brain sends a portion of Stem Cells to the so-called «lesion focus» and there they transform into cells of damaged brain tissues, replacing the sick ones.
In other words, Stem Cells can independently find the source of damage and the cause of the malfunctioning of the organs and systems of the body. They migrate to the source of a problem and cause a whole cascade of regenerative reactions there, restoring damaged functions. This fact allows the usage of Stem Cell Therapy for helping patients with diseases of the central nervous system, including for Cerebral Palsy.
It is important that the best results of Stem Cell treatment are seen in children. They have a greater regenerative potential compared to adults, the treatment with Stem Cells allows this potential to be strengthened and cause self-healing in the focus of brain damage
Since 2016, children with Cerebral Palsy have received Stem Cell Therapy in our clinics with pronounced and stable clinical results!
For an objective evaluation of the results of treatment in the clinic we have conducted an assessment of the dynamics of symptoms and the child’s conditions like central paresis; fine motor skills; self-care skills; psycho-emotional sphere; attention; visual functions, as well as the level of development of children with Cerebral Palsy in the main clinical group and the control group. The comparison was carried out according to the KID scale.
A positive effect was observed in each child: some became more attentive, some became more active, some became actively interested in others, and they began expressing their emotions and needs; muscle spasticity decreased, as a result of which the children began to walk independently.
Specialists at our clinics have developed a unique method of a combined approach to the treatment of Cerebral Palsy — Stem Cell Therapy.
There are 3 ways to introduce Stem Cells into the patient’s body:
With this simultaneous administration, Stem Cells from different sources enhance each other’s therapeutic effect and increase the duration of the treatment effect. The combination of several routes of administration allows the transport of Stem Cells to all target organs (central and peripheral nervous system, muscular apparatus). There they cause a whole cascade of regenerative processes. As a result, activation and formation of new cells of the nervous tissue occur, which replaces the damaged areas of the brain, providing a therapeutic effect on all symptoms of the disease.
The intravenous way of administration ensures the penetration of Stem Cells with blood flow to all organs and tissues of the body that are weakened by the disease and cause the normalization of the functioning of all body systems. Stem Cells are present in every human body. However, their introduction in a dosage million times higher than their normal amount in the body allows them to restore the myelin sheath of the affected nerve fibers and stop the overreaction of the immune system that this lesion causes. Such a large number of Stem Cells allows them to distribute both in the central nervous system and throughout the body, improving the function of all systems and organs.
In addition, clinical studies have found that the introduced Stem Cells can be modified (differentiated) into other cells, including nerve cells. By modification, Stem Cells are embedded between the cells of the nerve bundles, thereby replacing all the affected areas. This restores the process of transmitting the nerve impulse and leads to the reverse development of disease symptoms.
With intrathecal administration, Stem Cells are injected directly into the spinal space of the vertebral column. Thus, with the current of cerebrospinal fluid, they penetrate the blood-brain barrier and are fixed directly in damage to the brain and motor neurons. There, they stimulate regeneration processes, slow down the progression of the disease, and in some cases, restore lost functions. The introduction of Stem Cells into the spinal space slows down the process of destruction of motor neurons and promotes partial restoration of the structure of the spinal cord. Replacing dead neurons, Stem Cells reduce symptoms and improve motor disorders without causing a negative immune response in the body.
The intranasal way is the introduction of Stem Cells and exosomes (concentrate of regenerative substances that produce Sem Cells) to the patient by inhalation. In this way, the introduction of Stem Cells and exosomes penetrates directly into the brain through the vascular network of the nasal sinuses. The method can be used for correction of cognitive manifestations of the disease: it improves behavioral responses, speech, attention, mood, sleep, social adaptation, and most importantly, it is well tolerated by little patients.
We have a successful 10-year experience in studying the use of Stem Cells for the treatment of neurological diseases,so our experts concluded that the greatest effect in Cerebral Palsy is gained by the use of the patient’s own (autologous) and donor (allogenic) Stem Cells both alone or in combination with each other.
The Stem Cell Therapy program for Cerebral Palsy also includes complex physiotherapeutic procedures that improve the penetration of Stem Cells into the damaged areas and create conditions for their long-term functioning (hyperbaric oxygen therapy, electrical stimulation, reflexology, etc.).
During the treatment program, patients undergo a course of neurostimulation-activation of the function of nerve cells using unique equipment. Our project team specialists have participated in the development of this equipment.
NeoStim-3 : spinal neurostimulation.
Innovative stimulation of the spinal cord through transcutaneous action of electrical impulses on the neural networks of the spinal cord.
NeoStim-16: peripheral myoneurostimulation.
Transcutaneous functional electrical stimulation for the correction of pathological motor stereotypes
NeuroPort: translingual neurostimulation. Allows to effectively and non-invasively influence the brain directly during exercise therapy, cognitive training, and relaxation sessions. Thanks to such training, the patient gradually restores the function of sitting, standing, and walking which reduces spasticity, resumes free motor activity, improves cognitive functions, restores speech, normalizes sleep and emotional state, and overcomes psychomotor lag in children.
Also, the program includes classes with an instructor rehabilitologist under the program «Evolution of Movement» according to an individual plan, which allows the identification of pathological movement patterns, correct muscle tone, and postural reactions, and forms the correct biomechanics of movements in patients with impaired motor function. The specialist will offer corrective taping and recommendations for home correction of movement biomechanics.
The minimum duration of the program is 3 days. The procedure is performed on an outpatient basis, but if required or if desired by the patient, the program can be performed on an inpatient basis.
Depending on the patient’s condition (the stage of disease, the presence of complications and concomitant diseases, etc.), the doctors of our clinics can make changes and additions to the treatment program according to the patient’s needs.
We warn that the effectiveness of Stem Cell Therapy depends on many factors (the patient’s age, concomitant diseases, and complications, individual characteristics of the body, genetic predisposition, lifestyle, etc.), so the expected result of treatment may differ from the actual result. In addition, we draw attention to the fact that the recovery of patients after Stem Cell Therapy should be implemented as part of a comprehensive approach to treatment after regenerative cell therapy. Stem Cell Therapy can be combined with other therapeutic methods. This increases the effectiveness of the main therapy. Therefore, we recommend that you continue your rehabilitation and follow all your doctor’s advice on drug treatment of the disease in parallel with Stem Cell Therapy. This is a crucial point for achieving a sustainable result.
We provide the most comfortable conditions of stay and excellent client service to our patients:
free transfer (the patients are taken to the Clinic from railway stations or airports and back);
selecting and booking the most transport-accessible hotel (only accommodation is paid);
оur clinics have facilities for the comfortable stay of people with disabilities.
Our clinics have everything you need for treatment: our laboratory for the cultivation of Stem Cells, biobanks for storage, and the best specialists in Regenerative medicine who constantly improve their skills to help our patients with the most modern and safe methods.
We try to make our patients feel at home in the clinic and the entire treatment process goes smoothly.
You need to consult with the doctors to get complete information about the possibility of Stem Cell Therapy specifically in your case. Sign up for a free consultation with the specialists of the clinic and give your child the opportunity to live an active and full life!
We will do our best to help you!